This technology overview provides a brief, simplified description of how OmniLytics’ bacteriophage technology provides a unique treatment of bacterial disease and infection.
Our products contain bacteriophage as the primary active ingredient. Bacteriophage, or “phage” as they are known, are unique viruses that destroy specific types of bacteria in a process called lysing.
Phages are found everywhere and are part of our everyday lives. As the biological predator to bacteria, they are found on all common surfaces such as a desk or computer keyboard, and are always part of the food we eat and the water we drink.
While phages are technically classified as viruses, they are very different from the dangerous viruses we are familiar with such as those that cause AIDS or Influenza. Phages cannot infect any mammalian or human cells. They are considered a helpful part of our environment because they keep the world’s population of bacteria in check.
Humans have been exposed to bacteriophage since the beginning of time and have been the beneficiaries of their help in fighting off bacterial infections.
A phage is approximately 100 times smaller than a typical bacterium.
Bacteria, which cause many infectious diseases, are ubiquitous and exist everywhere. They too can be detected on virtually every surface of our planet. While bacteria can be beneficial, there are many varieties that are destructive and even dangerous.
The Lysing Process
Phages are chemically attracted to a specific bacterial hosts. This attraction is extremely specific, which enables OmniLytics to use phage in a variety of applications without affecting humans, animals, or even non-target bacteria.
When a phage encounters a bacterium, it attaches itself to the cell wall of the bacterium using its tail fibers.
Once a phage attaches to a bacterium, it penetrates the cell wall of the bacterium and inserts its own DNA, effectively taking over the cell and destroying the bacterium’s ability to function.
Once the phage’s DNA has been inserted into the bacterium, the DNA of the phage begins to replicate and assemble into new phage. This process continues at a very rapid pace.
When the replication of phage weakens the cell wall structure and exceeds the available space within the bacterium cell, the cell wall bursts and the new phage are released into the environment to encounter and destroy additional target bacteria in the same process.
Each time a bacterium is infected by a phage, approximately 100 new phage are produced.
Because this process continues until all available bacteria are destroyed, our products actually increase in effectiveness in an exponential manner.
Once all the target bacteria have been destroyed, the remaining phage break down into common biological particles and are absorbed back into the environment.
Through this process, phages are able to destroy harmful bacteria in a efficient, economical approach. Bacterial lysis is constantly happening all around us and is one of the most overlooked methods of combating bacterial diseases.
OmniLytics, Inc.’s proprietary formulas and processes optimize the use of bacteriophage technology for commercial applications.